Mike Doyle

Michael P. Doyle (Professor, University of Maryland) is the developer of “Doyle catalysts” – chiral dirhodium carboxamidates that are the most effective catalysts for highly stereoselective intramolecular reactions of diazoacetates that include C-H insertion and cyclopropanation. The fixed stereodefined geometry of these catalysts provides access to highly enantioenriched products in metal carbene reactions and, together with their low oxidation potentials, also affords capabilities for highly selective Lewis acid catalyzed reactions and efficient chemical oxidations with high turnover numbers and high selectivities. His research has encompassed physical organic chemistry, synthetic method development, the bioinorganic chemistry of nitrogen oxides and nitrosyls, and asymmetric syntheses.