Matthew Albritton

School: University of Florida
Mentor: Alex Grenning
Research: Ring Rearrangement Metathesis of Substituted Bicyclic Tetraenes to Yield Isoryanodane Cores
Sponsor: Biogen & Janssen

Finn Beruldsen

School: Hendrix College
Mentor: Heidi Dahlmann
Research: Optimization of Organocatalyzed Carbonyl- Olefin Metathesis Reactions
Sponsor: Allergan & Morphic

Andrew Champlin

School: Bucknell University
Mentor: Hasan Arslan
Research: Synthesis of an Anthracene-Based Betaine Dye and a Study of its Electrochemical and Photophysical Properties
Sponsor: Wuxi AppTec

Sriyankari Chitti

School: University of Illinois at Urbana-Champaign
Mentor: Martin Burke
Research: Carbenoid-Boronate Building Blocks Enable Iterative Cross Coupling
Sponsor: Vertex

Crystal Chung

School: Univ. California, Irvine
Mentor: Vy Dong
Research: Rh-catalyzed Asymmetric Allylation of Nitro-carbonyls
Sponsor: Pfizer

Julian Cizmic

School: San Diego State University
Mentor: Byron W. Purse
Research: Synthesis and Photophysics of the DEA-tCc Fluorescent Nucleoside Analogue
Sponsor: Pfizer

Mitchell E. Daneker

School: University of Delaware
Mentor: Mary P. Watson
Research: A New Use for the Strecker Reaction as a Pathway to Pyridinium Chemistry
Sponsor: Pfizer

Jessica Gallawa

School: Western Washington University
Mentor: James R. Vyvyan
Research: Total Synthesis of Rupestines L and M
Sponsor: Pfizer

Gabriel Herrera

School: New York University
Mentor: Tianning Diao
Research: Photocatalytic Tryptophan Modification in Peptides and Proteins in Aqueous Media
Sponsor: Pfizer

Olivia Langner

School: University of California, Santa Barbara
Mentor: Bruce Lipshutz
Research: New Rules for Asymmetric Reactions in Aqueous Micellar Media
Sponsor: Bristol-Myers Squibb

Mira Milic

School: Univ. of California, Davis
Mentor: Annaliese Franz
Research: Synthesis of Chiral-at-Silicon 1,3-Disiloxanediols via Small Molecule Directed Silylation
Sponsor: GlaxoSmithKline

Henry O’Callaghan

School: University of Nebraska-Lincoln
Mentor: David B Berkowitz
Research: Design and Synthesis of a New Class of Potential Human Serine Racemase Inhibitors
Sponsor: Takeda

Tiana Saak

School: Washington University in St. Louis
Mentor: Jonathan Barnes
Research: Studying the Effects of Sequence Control in Photodynamic Synthetic Polymers
Sponsor: Lilly

Ben Stemen

School: North Carolina State University
Mentor: Joshua G. Pierce
Research: Synthesis of Synoxazolidinone C as a Novel Antibiotic Lead
Sponsor: Merck

Jonathan Wong

School: Univ. of California, Los Angeles
Mentor: K. N. Houk
Research: Vinyl Cations: A Computational and Experimental Investigation
Sponsor: Merck

Johnny Wang

School: Boston College
Mentor: James Morken
Research: Z-Alkenyl Boronates by a Boron-Petersen Reaction
Sponsor: Bristol-Myers Squibb

Yotam Ashkenazi

Sponsor: Pfizer
School: University of Connecticut
Mentor: Mark Peczuh
Research: Nature Inspired Modular Synthesis of Hernandezine

Roukaya El Mokadem

Sponsor: Celgene
School: Oklahoma State University
Mentor: Jimmie Weaver
Research: Taming Two (photocatalytic) Transformations; Reductive Alkenylation and Isomerization of 2-Bromoazoles

Clara Ellis

Sponsor: Vertex
School: University of Southern Mississippi
Mentor: Matthew G. Donahue
Research: Enantioselective Synthesis of Piperidine Derivatives Through an Enyne Metathesis

Montgomery Gray

Sponsor: Takeda
School: Ohio State University
Mentor: T. V. (Babu) RajanBabu
Research: Hemilabile Ligands for Improved Selectivity in Cobalt Catalyzed Reactions of Alkenes

Christopher Hanneman

Sponsor: Lilly
School: University of Illinois at Urbana-Champaign
Mentor: Scott Denmark
Research: A Strategy for the Cross-Coupling of Heterocycles

Yelin Jung

Sponsor: Pfizer & Biogen
School: Bryn Mawr College
Mentor: Bill Malachowski
Research: Development of Complex Chiral Carbazole Analogs via the Enantioselective Birch-Curtius-Heck Reaction Sequence

Austin King

Sponsor: Merck & Janssen
School: Michigan State University
Mentor: Robert E. Maleczka, Jr.
Research: Isolation of Asymmetrical Double-Decker Oligomeric Silsesquioxanes

Amanda Melanese

School: California State University San Marcos
Mentor: Robert Iafe
Research: Gold(I)-Catalyzed Friedel-Crafts-type reaction to afford substituted benzimidazoles
Sponsor: Pfizer

Kellie Stellmach

Sponsor: WuXi AppTec
School: Macalester College
Mentor: Dennis D. Cao
Research: Synthesis and Characterization of Angled Benzene Diimides as Building Blocks for Linear Azaacenes

Jordan Thompson

Sponsor: Merck
School: University of California, Berkeley
Mentor: Thomas Maimone
Research: Total Synthesis of 6-epi ophiobolin A

Joey Tuccinardi

Sponsor: Pfizer
School: Boise State University
Mentor: Don Warner
Research: Synthesis of Small Molecules to Inhibit a Pro-Metastatic Cytokine

St. John Whittaker

Sponsor: Pfizer & Mirati
School: University of Scranton
Mentor: Arthur Catino
Research: Enantioselective Synthesis of Tetraarylmethanes using Chiral Brønsted Acids

Elise Brutschea

Sponsor: Pfizer
School: Saint Joseph’s University
Mentor: Mark Forman
Research Project: Electroreduction: A Greener Alternative to the Synthesis of the Pyramidalized Alkene Pentacyclo[4.3.0.0 ^2,4 .0 ^3,8 .0 ^5,7 ]non-4-ene

Amy Chan

Sponsor: Pfizer
School: Yale University
Mentor: Jonathan Ellman
Research Project: Potent and Selective Isoquinuclidine Ligands to G-Protein Coupled Receptors

Rania Daboul

Sponsor: Merck
School: University of Michigan
Mentor: Corinna Schindler
Research Project: Application of catalytic carbonyl olefin metathesis reactions to the asymmetric synthesis of sesquiterpene natural products

Jake Grabowski

School: Illinois State University Mentor: Andy Mitchell
Research Project: Feist-Bénary Furan Synthesis Toward the Total Synthesis of Toxicodenane A
Sponsors: Pfizer and Biogen

Noel Jameson

Sponsor: Amgen
School: Occidental College
Mentor: Roul Navarro
Research Project: Total Synthesis of Swerilactone A via a Novel Electrophilic Dearomatization Reaction

Spencer Lawson

Sponsor: Pfizer
School: University of Delaware
Mentor: Donald Watson
Research Project: Development of a Nickel-Catalyzed Aza-Heck Cyclization

Gina Partipilo

Sponsor: Pfizer
School: Univ. of Illinois, Urbana-Champaign
Mentor: Jefferson Chan
Research Project: Reversible Probe for the Detection of Nitric Oxide in vivo Using Photoacoustic Imaging

Eric Rizzo

Sponsor: Pfizer
School: Stony Brook University
Mentor: Ming-Yu Ngai
Research Project: Chiral Catalysts for Asymmetric Visible-Light Photocatalytic Reactions

Matthew Thompson

Sponsor: Merck
School: Case Western Reserve University
Mentor: Drew Adams
Research Project: Developing Selective Covalent Inhibitors through the Synthesis of Novel Sulfonyl-Fluoride Probes

Amanda Cowfer

Sponsor: Pfizer
School: University of Illinois
Mentor: Paul Hergenrother
Research Project: Synthesis and Biological Evaluation of a Compound Library Derived from Lycorine

Alex Cusumano

Sponsor: Pfizer
School: North Carolina State University
Mentor: Joshua Pierce
Research Project: Utility of the 3-Hydroxy-1,5-dihydro-2H-pyrrol-2-one Scaffold in the Synthesis of alpha-Quaternary Centers Containing Beta-Homo Prolines and Beta-Lactams

Katherine Forbes

Sponsor: Merck
School: Occidental College
Mentor: Jeffrey Cannon
Research Project: Synthesis of Furanolactone Motifs through a Photocatalyzed Ketyl Radical Cyclization

Margaret McEwan

Sponsor: Pfizer
School: Christopher Newport University
Mentor: Jeffrey Carney
Research Project: Towards the Total Synthesis of Torreyunlignans A-D

Lucus Oxtoby

Sponsor: Pfizer
School: Wisconsin-Madison
Mentor: Jennifer Schomaker
Research Project: Investigating Analogs of Eflornithine, an Irreversible Inhibitor of Ornithine Decarboxylase

Maximilian Palkowitz

Sponsor: Merck
School: Boston College
Mentor: James Morken
Research Project: Stereoselective Synthesis of Cyclopropyl- and Cyclobutylboronic Esters via Diastereoselective alpha-Boryl-Carbanion Cyclizations

Ambarneil Saha

Sponsor: Pfizer
School: Cornell University
Mentor: Song Lin
Research Project: Recycling CO2 for Amino Acid Synthesis

Holt Sakai

Sponsor: Merck
School: Yale
Mentor: Timothy Newhouse
Research Project: Nickel-Catalyzed Intramolecular alpha-Vinylation for the Synthesis of Bicyclic Systems

Emma Streff

Sponsor: Merck
School: Washington University in St. Louis
Mentor: Vladimir Birman
Research Project: Amidine-Based Catalysts with Enhanced Nucleophilicity: Synthesis, Study, and Applications

Harrison Besser

Sponsor: Pfizer
School: Harvard University
Mentor: Eric Jacobsen
Research Project: Development of an Iron Catalyst for Carbon-Hydrogen Oxidation

Hannah Burdge

Sponsor: Merck
School: Towson University
Mentor: Keith Reber
Research Project: Total Synthesis of Cladosin C

Shivansh Chawla

Sponsor: Merck School: Cornell University
Mentor: Yimon Aye
Research Project: Synthesis of a Fluorescent Redox-Targeting Toolset for Use in Multicellular Organisms

Corrine Elliott

Sponsor: Pfizer
School: University of Kentucky
Mentor: Susan Odom
Research Project: Steric Manipulation of Electrochemical Potentials in Conjugated Organic Molecules

Chris Fritschi

Sponsor: Pfizer
School: Niagara University
Mentor: Luis Sanchez
Research Project: Developing a Synthetic Route to Caramboxin, a Rare Bioactive Non-peptidic Amino Acid

Anneliese Gest

Sponsor: Pfizer
School: Macalester College
Mentor: Leah Witus
Research Project: Development of a Colorimetric Assay for the Screening of Peptide Catalysts

Evan Hurlow

Sponsor: Merck
School: University of Utah
Mentor: Jon Rainier
Research Project: The Derivatization of an Aggregate-Busing Quinone-Amino Acid Conjugate

Tyler Pabst

Sponsor: Merck
School: Youngstown State University
Mentor: Douglas Genna
Research Project: Transition Metal-Mediated C-CO ₂ Coupling Reactions for the Synthesis of Industrial Carbon Feedstocks

Tekenari Tienabeso

Sponsor: Pfizer
School: University of Oklahoma
Mentor: Indrajeet Sharma
Research Project: Synthetic Access to the Psurotin Core via a Diazo-OH Insertion/Conia-Ene Cascade

Adonis Cruz

Sponsor: Merck
School: Hobart and William Smith Colleges
Mentor: Justin Miller
Research Project: Solid-Phase Total Synthesis of Cysteine-Containing, Depsipeptidic Natural Products and Analogs

Carl Ferber

Sponsor: Pfizer
School: University of San Diego
Mentor: Timothy Clark
Research Project: Stereoselective Diboration/Homologation Sequence of Aldehydes using Lithiated Epoxides

Tyler Fulton

Sponsor: Pfizer
School: Bucknell University
Mentor: Michael Krout
Research Project: Development of Copper Mediated Conjugate Addition Reactions Towards Complex Molecule Synthesis

Catherine McGeough

Sponsor: Merck
School: Smith College
Mentor: Kevin Shea
Research Project: Synthesis and Characterization of Derivatives of Neurole nin A and B

Amanda O’Loughlin

Sponsor: Pfizer
School: University of Nevada, Reno
Mentor: Wesley A. Chalifoux
Research Project: Efficient Synthesis of Bicyclo[4.4.0]decanes by Tandem Double Diels-Alder

Melissa Ramirez

Sponsor: Merck
School: University of Pennsylvania
Mentor: Gary A. Molander
Research Project: B-X Functionalization of Borazarobenzofurans and Bioisosteric Activity of Azaborines

Shafer Soars

Sponsor: Pfizer
School: Illinois College/ Yale University
Mentors: Brent Chandler/Scott Miller
Research Project: Development of a Catalyst Controlled Enantioselective and Diastereoselective Rauhut-Currier Reaction

Jessica Spradlin

Sponsor: Pfizer
School: Tufts University
Mentor: Clay Bennett
Research Project: Synthesis of the Pentasaccharide Fragment of Saquayamycin Z

Fuhua Zhao

Sponsor: Merck
School: Stoney Brook University
Mentor: Ming-Yu Ngai
Research Project: Trifluoromethoxylation of Heteroarenes

Alexander Cleveland

Sponsor: Pfizer
School: Tennessee Technological University
Mentor: Jessie Carrick
Research Project: Investigation of the asymmetric induction of the hetero-Diels-Alder reaction with β-alkoxyaldehydes and Chiral chromium(III) catalysts

Nicolle Doering

Sponsor: Pfizer
School: University of California Santa Barbara
Mentor: Armen Zakarian
Research Project: Synthesis of Imidazoline LOXL2 Analogs

Richard Liu

Sponsor: Pfizer
School: Harvard University
Mentor: Eric Jacobsen
Research Project: Small Molecule Hydrogen-Bond Catalysts for Asymmetric C–N Bond Formation

Moises Morales

Sponsor: Pfizer
School: Washington State University
Mentor: Philip Garner
Research Project: A β-Aspartyl Thioester Building Block for Convergent Glycosylative Ligation of Peptides

Julia Murphy

Sponsor: Pfizer
School: Swarthmore
Mentor: Robert Paley
Research Project: Azaspirocycle Formation Directed by a Planer Chiral iron(O) Tricarbonyl diene complex

Riley Svec

Sponsor: Cubist
School: University of Iowa
Mentor: Hien Nguyen
Research Project: Synthesis and affinity studies of mannose-derived glycopolymers for binding to antibody 2G12 which recognizes the gp120 epitope within the HIV envelope

Pete Barnes

Sponsor: Genentech/Roche
School: Boise State University
Mentor: Don Warner
Research Project: Toward a Convergent Synthesis of Aziridinomitosenes

Craig Burt

Sponsor: Pfizer
School: Williams College
Mentor: Thomas Smith
Research Project: Asymmetric Synthesis of Enigmazole A

Masha Elkin

Sponsor: The ACS Organic Division
School: Washington University
Mentor: Vladimir Birman
Research Project: An Efficient and Flexible Synthetic Route to Chiral Ligands

Michelle Ferreira

Sponsor: Pfizer
School: Swarthmore College
Mentor: Liliya Yatsunyk
Research Project: Synthesis of Novel Polyamide Derivatives of Protoporphyrin-IX And Mesoporphyrin-IX As Potential G-Quadruplex Stabilizers

Terry Huh

Sponsor: Pfizer
School: Bryn Mawr College
Mentor: Bill Malachowski
Research Project: Synthesis of Bicyclic Rings with Quaternary Centers through Sequential Birch Reduction-Alkylation and Cycloisomerization

Samuel Levi

Sponsor: Merck
School: University of Pennsylvania
Mentor: Jeffrey Winkler
Research Project: The Design and Synthesis of Novel Chloroquine Derivatives to Block Autophagy in Cancer Cells

Lydia Wolfe

Sponsor: Cubist
School: St. Olaf College
Mentor: Dipannita Kalyani
Research Project: Nickel Catalyzed Carbon-Carbon Bond Formation

Ronald Besandre

Sponsor: Division of Organic Chemistry
School: University of Houston
Mentor: Jeremy A. May
Research Project: Synthesis of Indoles from α-Arylketones and Amines using Copper (I)

Alexander Burckle

Sponsor: Pfizer
School: University of Utah
Mentor: Matthew S. Sigman
Research Project: Tandem Cross-Coupling using Heck Substrates and Selective β-hydride Elimination to Generate Vinyl Halides

Blake Daniels

Sponsor: Division of Organic Chemistry
School: University of Chicago
Mentor: Hisashi Yamamoto
Research Project: TBOx-Catalyzed Nitroso Hetero-Diels-Alder Reactions

Bennett Ferris

Sponsor: Cubist
School: Brown University
Mentor: Jason Sello
Research Project: Investigation of a Domino Reaction in the Target and Diversity-Oriented Synthesis of a Novel Antibacterial Agent

Drew Heitz

Sponsor: Pfizer
School: University of Iowa
Mentor: Hien Nguyen
Research Project: Rhodium-Catalyzed Amination of Allylic Trichloroacetimidates and the Development of Antiretroviral Analogues

Rebecca Johnson

Sponsor: Roche
School: Barnard College
Mentor: Christian Rojas
Research Project: Using a Copper (II) Catalyst to Achieve Stereo-and Chemoselective Glucal 3-Carbamate Amidoglycoslation Reactions

Hilary Kerchner

Sponsor: Pfizer
School: University of Delaware
Mentor: Mary P. Watson
Research Project: Enantioselective, Copper-Catalyzed Additions of Arylboronic Acids to Chromene Acetals

Anna Koster

Sponsor: Division of Organic Chemistry
School: University of Nevada, Reno
Mentor: Christopher S. Jeffrey
Research Project: Synthesis of Aldol Products through Electrophilic Aromatic Substitution of Aza-Oxyallyl Cation Intermediates

Matthew Landry

Sponsor: Merck
School: Princeton University
Mentor: Abigail Doyle
Research Project: Total Synthesis of Paecilospirone

Jaron Mercer

Sponsor: Pfizer
School: Harvard University
Mentor: Andrew G. Myers
Research Project: A New Synthetic Route to Substituted Tetrahydroisoquinolines

Richard Thornbury

Sponsor: Division of Organic Chemistry
School: University of Illinois-Urbana Champaign
Mentor: Scott E. Denmark
Research Project: Asymmetric Chlorinations of Alkenes Using Chiral Quaternary Ammonium Polyhalide Salts

Alice Wong

Sponsor: Pfizer
School: Swarthmore College
Mentor: Robert Paley
Research Project: Diastereoselective Allyl Silane-Iminium Ion Cyclization Directed by a Planar Chiral Iron (0) Tricarbonyl Diene Complex

Derek Ahneman

Sponsor: Division of Organic Chemistry
School: University of Delaware
Mentor: Donald Watson
Research Project: Developing a catalyst for asymmetric alcohol alkylation

Catriona E. Blunt

Sponsor: Novartis
School: Smith College
Mentor: Kevin Shea
Research Project: Scope of a tandem Diels-Alder/Pauson-Khand synthesis for tetracycles

Adam N. Boynton

Sponsor: Pfizer
School: Trinity College
Mentor: Timothy Curran
Research Project: Coordination of a peptide B-turn mimetic to tungsten: possible applications for the study of B-sheets

Zachary Brill

Sponsor: Division of Organic Chemistry
School: Columbia University
Mentor: Scott Snyder
Research Project: Total synthesis of Caraphenols B and C and related natural products

Taryn Campbell

Sponsor: Pfizer
School: Connecticut College
Mentor: Timo Ovaska
Research Project: Studies toward the total synthesis of Frondosin D

Noelle Catarineu

Sponsor: Roche
School: New York University
Mentor: James Canary
Research Project: Synthesis and study of redox- active chiroptical molecular switches

Marc Giesener

Sponsor: Division of Organic Chemistry
School: Northwestern University
Mentor: Fraser Stoddart
Research Project: Multiple successive post synthetic modifications on metal- organic frameworks

Emily Hartman

Sponsor: Cubist
School: Brown University
Mentor: Amit Basu
Research Project: A chemical genetic analysis of galactose biochemistry in growing pollen tubes

David Kaphan

Sponsor: Pfizer
School: University of Rochester
Mentor: Robert Boeckman
Research Project: Studies toward the diversification Of Diels-Alder Reactions of cyclic isoimidium salts

Victor W. Mak

Sponsor: Amgen
School: University of California, Irvine
Mentor: Kenneth Shea
Research Project: A concise total synthesis of (-)-Stenine

Wystan Neil Palmer

Sponsor: Division of Organic Chemistry
School: Swarthmore College
Mentor: Robert Paley
Research Project: Diastereoselective synthesis of bis-spiroketals directed by planar chiral 2-sulfinyl diene iron(0) tricarbonyl complexes

Ian Pendleton

Sponsor: Pfizer
School: Eastern Michigan University
Mentor: Harriet Lindsay
Research Project: Determining the origins of stereocontrol in the Lewis acid-mediated aza-Cope rearrangement-Mannich cyclization of conformationally mobile iminium cations

Ryan Spencer Shinabery

Sponsor: Pfizer
School: University of Arkansas, Fayetteville
Mentor: Nan Zheng
Research Project: Photocatalyzed [3+2] cycloaddition of bicyclic cyclopropylamines with olefins by a ruthenium (II) complex

Alexander W. Sun

Sponsor: Cephalon
School: University of Pennsylvania
Mentor: Amos B. Smith III
Research Project: Synthesis of HIV-1 entry inhibitors: region II/III analogs of NBD-556

Nadia C. Abascal

Sponsor: Boehringer Ingelheim
School: Barnard College
Mentor: Christian Rojas
Research Project: A soluble iodosobenzene derivative for 2-amino sugar synthesis

Juan Carlos Baso

Sponsor: Organic Division
School: University of South Florida
Mentor: Jon Antilla
Research Project: Enantioselective reduction of imines; A strategy for the construction of the Dragmacidin core and potential structural analogues

James Beckett

Sponsor: Organic Division
School: Kenyon College
Mentor: John Hofferberth
Research Project: Exploring the versatility of a novel route to the cyclopenta[c]pyridine substructure

Megan Marie Blewett

Sponsor: Pfizer
School: Harvard University
Mentor: EJ Corey
Research Project: C-H functionalization with metallosalen complexes

Kurt James Cox

Sponsor: Organic Division
School: University of Arizona
Mentor: Indraneel Ghosh
Research Project: A synthetic bivalent approach for targeting protein kinases

Mary E. Daub

Sponsor: Cubist
School: Williams College
Mentor: Thomas Smith
Research Project: Asymmetric synthesis of Jerangolid D

Althea Gaffney

Sponsor: Pfizer
School: Swarthmore College
Mentor: Robert Paley
Research Project: Planar chiral 2-sulfinyldiene iron( 0) tricarbonyl complexes as a platform for diastereo- selective synthesis of spiroketals

Anthony S. Grillo

Sponsor: Pfizer
School: University of Michigan
Mentor: Masato Koreeda
Research Project: Development of a novel chiral heterocyclic carbene to be used in ruthenium catalyzed olefin metathesis

Dennis Hu

Sponsor: Organic Division
School: Northwestern University
Mentor: Regan Thomson
Research Project: Synthesis and structure / functional studies of Streptorubin B

Eduardo V. Mercado

Sponsor: Roche
School: University of California, Santa Barbara
Mentor: Thomas Pettus
Research Project: Synthetic approach toward unsymmetrical napthoquinone natural products: B-rubromycin, christazarin, echinochrome A and echinamines B

Jason Pflueger

Sponsor: Novartis
School: Columbia University
Mentor: Scott Snyder
Research Project: The total synthesis of Heimiol A, a Resveratrol-based natural product

James Phelan

Sponsor: Pfizer
School: Grinnell College
Mentor: Stephen Sieck
Research Project: Investigation of N-acyl nitrones and their application in isoxazolidine synthesis

Katie Schaefer

Sponsor: Pfizer
School: University of Utah
Mentor: Matthew Sigman
Research Project: Three dimensional mathematical modeling of modular pyridine ligands for the enantioselective alkylation of ketones

Jonathan Schultz

Sponsor: Organic Division
School: North Dakota State University
Mentor: Gregory Cook
Research Project: Catalytic enantioselective synthesis of chiral allylboronates

Justin Su

Sponsor: Pfizer
School: The University of Texas at Austin
Mentor: Stephen Martin
Research Project: Synthesis of a diverse Protoberberine- based small molecule library for biological screening

Valerie Angell

Sponsor: Organic Division
School: Union College
Mentor: James Adrian
Research Project: Developing methods for preparing and testing libraries of pyrrolidine-triazoles: a new class of organocatalysts

Joseph Michael Azzarelli

Sponsor: Symyx Technologies
School: Stanford University (Montana State University)
Mentor: Barry Trost
Research Project: Cationic palladium (II) directed stereoselective β-glycosylations

Ross W. Cheloha

Sponsor: American Chemical Society
School: University of Nebraska-Lincoln
Mentor: David Berkowitz
Research Project: Chemoenzymatic entry into dihydrocinnamayte building blocks and their synthetic elaboration: control of absolute and relative stereochemistry

Andrew Chung

Sponsor: Organic Division
School: Harvey Mudd College
Mentor: David Vosburg
Research Project: Biomimetic synthesis of the Endiandric Acids

Rachel Dorset

Sponsor: Sepracor
School: Smith College
Mentor: Kevin Shea
Research Project: Scope and limitations of cationic Diels-Alder dienophiles stabilized by cobalt-complexed alkynes

Nathaniel Erskine

Sponsor: Organic Division
School: Swarthmore College
Mentor: Robert Paley
Research Project: Diastereoselective synthesis of spiroketals using planar chiral iron(0) tricarbonyl complexes

Reid M. Faylor

Sponsor: Organic Division
School: Xavier University
Mentor: Richard Mullins
Research Project: Asymmetric conjugate addition for synthesis of pilocarpine and related compounds

Michelle Grau

Sponsor: Pfizer
School: University of San Diego
Mentor: Debbie Tahmassebi
Research Project: Synthesis and structural studies of a novel nucleoside analogue

Joshua Green

Sponsor: Cubist Pharmaceuticals
School: Harvard University
Mentor: Tobias Ritter
Research Project: Development of a reaction discovery methodology employing mass spectrometry

Jonathan James Hulce

Sponsor: Pfizer
School: University of Vermont
Mentor: Paul Krapcho
Research Project: A potential therapy for neurologic disorders via inhibition of the endogenous neurotoxin-like protein, “Lynx”

Lauren E. Kennedy

Sponsor: Wyeth
School: University of Pennsylvania
Mentor: Gary Molander
Research Project: Deprotection of potassium trifluoroborates to the corresponding boronic acids

Cameron Moore

Sponsor: American Chemical Society
School: Western Washington University
Mentor: Timothy Clark
Research Project: Copper-catalyzed diboration of ketones; facile synthesis of tertiary α-hydroxy boronate esters

Joseph Nagano-Gerace

Sponsor: Pfizer
School: Brown University
Mentor: Christopher Seto
Research Project: Unlocking glycosidase using an assay of synthetic fluorescent substrates

Andy I. Nguyen

Sponsor: Pfizer
School: University of California, Irvine
Mentor: Alan Heyduk
Research Project: Developing tantalum (V)-imido complexes with redox-active ligands for catalytic amination of C-H bonds and aziridination of olefins

Shreyas Shah

Sponsor: Organic Division
School: Rutgers University
Mentor: Ki-Bum Lee
Research Project: Multivalent nanoparticles as potent epidermal growth factor receptor (EGFR) inhibitors for glioblastoma multiforme (GBM)

Shannon Stone

Sponsor: Novartis
School: Brown University
Mentor: Amit Basu
Research Project: Click chemistry to visualize the carbohydrates behind the growth of pollen tubes

The SURF made me realize the impact and ubiquity of chemical science. As someone who chose to study chemistry simply because “I like it” and who has no close relatives who are scientists, I had no idea about the extent and impact that chemistry has. Meeting novel scientists in the field and their journey got me really excited about pursuing chemistry as a career. It got me thinking about where my path might align or differ from those individuals and how I can develop tangible goals on entering the field of chemistry. Being introduced to the young scientists in my fellow SURF awardees and the way they addressed complex chemical problems was inspiring. Indeed, their unique backgrounds and extraordinary passion for laboratory science stood out. College is a time when a lot of individuals may question their path and purpose. The SURF really helped affirm these things for me.

I learned that managing a project is hard. It takes patience and time, and what you set out to do is not always what you will end up doing. I learned about interacting in a professional environment, having deadlines, and planning ahead for future problems in my project.

After spending two years in laboratories at Berkeley, I had always wondered what the structure of companies in industry looked like. Seeing Merck and the different disciples and ways they operate was immensely helpful because I had never gotten to see it before. They are surely leaders in the field for doing novel research and having the latest technologies. The site visit was another way that got me excited about pursuing chemistry and having access to the type of research that Merck does and the beautiful network of scientists that it encapsulates.

The DOC SURF program allowed me to focus entirely on my research this summer. This allowed me to experience what research can truly be like without the distractions of another job/responsibilities. Solely focusing on research allowed me to make a large amount of progress in my summer project, something that I could not have done without the DOC SURF program. Most importantly, the DOC SURF program allowed me to have a taste of what graduate school will really be like in terms of the hours that I put into the lab. It showed me that I both enjoy treating the lab like a full time job and that I am capable of doing it. This summer allowed me to learn many new techniques in both synthetic and physical organic chemistry, but perhaps most importantly, I learned how to present my research in a concise way to those who had never seen it before. The site visit to Merck was a fantastic experience. Being able to see how chemistry was done in an industrial environment was amazing. The fact that the research and discovery process can be as streamlined as it was while also producing excellent results and a safe working environment was fantastic to see. Overall, the DOC SURF program was an amazing experience!

I was honored to have been awarded the SURF. My summer research taught me about project planning, execution of that strategy, and how to adapt to data which challenged the initial proposal. The summer also taught me how to tell the story of my group’s work and present an idea. The site visit left me in awe at the scale of the work done at Merck, in the highly sophisticated methods their researchers use to accomplish their goals, and in the sense of community between colleagues and competitors. The people I met were highly inspirational and it was a pleasure to get to know them.

SURF allowed me the chance experience what graduate school is like. Doing research all day, learning new things, it made me even more sure than ever that graduate school is where I’m headed after this year. It also gave me a chance to learn more about a career in industry. I didn’t know much about industry before the site visit to Merck, and I could not ask for a better introduction. SURF also allowed me to connect with people who are like me. People that love organic chemistry, love research, and want to use chemistry in their life beyond college.

This summer gave me a taste of what grad school life is like. I knew I want to go to graduate school after this year, but this summer truly showed me what it was like to dedicate your life to your research project. You come in to lab, you do research, you meet with your PI and lab mates, you make progress on your project. I loved every second of it. Regardless of what I actually ended up accomplishing on my project, I am very grateful for SURF for allowing me this opportunity to get even a small part of what my life will look like after this year.

Going to Merck was definitely one of my favorite things about SURF. Before the site visit, I didn’t really know much about the industry career path. I may not have learned the roles of every single person working in an industry setting such as Merck, but I got a pretty good idea and I honestly could not have asked for a better introduction. It has definitely made me seriously think about industry as a career choice after graduate school.

Through the SURF program, I was allowed to focus solely on my research full time which turned my passion for organic chemistry into a passion for research. This summer confirmed my desire to attend graduate school in support of continuing my career in drug development and discovery. Going to Merck was an incredibly insightful experience in which I was able to speak with skilled scientists and get a feel for a real-world industry setting. In addition, presenting my research matured my ability to communicate and collaborate ideas with professionals as well as my fellow awardees from across the country. The ACS DOC program ultimately motivated and inspired me to continue to pursue pharmaceutical research with the goal of helping people all around the world.

The SURF program allowed me to continue to engage in my passion for chemical research. This summer, I had the opportunity to explore the nuances and complexities of my research project, and see the bigger picture of how it fits into the field of organic electronics. My summer research also enabled me to collect enough data to present an honors project this spring semester, and taught me how to communicate clearly and concisely the results of my research, be it through a paper, presentation, or poster.

The site visit at Merck was really eye-opening, as it showed me how many of the same techniques I use in my academic research lab are also used in an industrial setting. It was amazing to see all of the state-of-the-art instrumentation that is used to improve efficiency and results. I also found it very valuable to talk with professionals during the site visit and learn more about their paths through academia and industry. These interactions provided me with a lot of insight that is helpful as I prepare for my future career in chemistry.

The SURF program gave me a wonderful opportunity to conduct graduate level research while still an undergrad which adds to my laboratory expertise. The experience gained under the SURF program makes me very marketable moving forward in my life.

The summer research opportunity thought me that nothing in research is easy. Researchers have to return to the lab day after day not knowing what this week’s experiments might produce, whether or not their results will be good, and all the while they have to be designing and approaching problems from new directions. However, research is a dynamic experience which is extremely rewarding academically, personally, intellectually, and there is nothing else quite like it.
It was impressive to see the (Merck) facilities and tools used on site for advanced pharmaceutical research.

Thanks to SURF, I had an amazing opportunity to work in an organic chemistry lab under Dr. Malachowski which was really eye-opening and intellectually stimulating. SURF program allowed me to see how research is greatly needed and significant in scientific discovery for everyone’s benefit. It really allowed me to see the big picture of the work that I was doing in lab and made me appreciate current scientists and researchers who have conducted so many reactions for us to utilize and build up on. It affirmed my passion for chemistry and showed wide range of chemical reactions that are being studied outside of the textbooks.

I learned that research takes so much patience and effort. Although I have taken a laboratory course, the procedure was all laid out for us and it was easy to follow. And it always yielded a desired product! However, behind every wonderfully carried out reaction, there are so many failed reactions and mechanisms that scientists have explored. As I conducted my own research, I realized it takes so much thinking and brainstorming behind the benchwork. Often our reaction would not work and we would have to go back to the beginning of our synthesis and rethink through the problem. There are so much intentionality and problem-solving involved in laboratory research. Through summer research I was able to greatly enhance not only my laboratory skills but also soft skills such as communication, working with team members, and organization skills.

The site visit (Merck) really allowed me to see and realize what kind of effort and work goes into designing and making a drug that people use on a daily basis. Listening to process chemist and medicinal chemist talk about their research demonstrated that what I do in the lab is translated to a pharmaceutical company. Additionally, so many scientists offered feedback and possible solutions to the problem I have with my current project and it was very encouraging to see that everyone is working towards the same goal. It was inspiring to see products of chemistry being tested and used. I’m so thankful for the mentorship and encouragement I’ve received at the site visit.